Expression, crystallization and structure elucidation of γ-terpinene synthase fromThymus vulgaris
نویسندگان
چکیده
منابع مشابه
Expression, crystallization and preliminary X-ray crystallographic analysis of cystathionine γ-synthase (XometB) from Xanthomonas oryzae pv. oryzae.
Cystathionine γ-synthase (CGS) catalyzes the first step in the transsulfuration pathway leading to the formation of cystathionine from O-succinylhomoserine and L-cysteine through a γ-replacement reaction. As an antibacterial drug target against Xanthomonas oryzae pv. oryzae (Xoo), CGS from Xoo (XometB) was cloned, expressed, purified and crystallized. The XometB crystal diffracted to 2.4 Å reso...
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Cystathionine γ-synthase (CGS) is a transulfurication enzyme that catalyzes the first specific step in L-methionine biosynthesis by the reaction of O(4)-succinyl-L-homoserine and L-cysteine to produce L-cystathionine and succinate. Controlling the first step in L-methionine biosythesis, CGS is an excellent potential drug target. Mycobacterium ulcerans is a slow-growing mycobacterium that is the...
متن کاملStructure elucidation and chemistry of novel diterpenoids from Euphorbia plants of Iran
Plants of the genus Euphorbia have been investigated for different bioactive natural products. I have isolated several new and bioactive diterpenoids from different species of Euphorbia of Iran with myrsinane type skeleton. The structure of the compounds was determined using high resolution mass spectroscopy, 1 D and 2 D NMR spectral data. The stereochemistry of the diterpenoids was determined ...
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ژورنال
عنوان ژورنال: Acta Crystallographica Section F Structural Biology Communications
سال: 2016
ISSN: 2053-230X
DOI: 10.1107/s2053230x15023043